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Pharmaceutical manufacturing

The application of electrolyzed oxidizing water

Electrolyzed oxidizing water named EOW has many properties alike high ORP,low PH value,active oxygen,low concentration active chlorine and HCLO.It has the strong and rapid disinfect function to kill microbe.It is the main physical and the minor chemical new type disinfectant without any harmful residue after disinfecting.EOW is invented by Japan in 1990 as the disinfectant to kill MRSA.Through many years’ research and practice,people has the census for its effectiveness,safeness non residue and friend-environment properties and applies into the medical industry alike disinfect for endoscope,hands,surrounding and hemodialysis device.Here is the ideal effect on disinfect of endoscope, operation room,apparatus and so on in hospital,when it reach China market in 1990.

Here is the description

1.generated principle

EOW is generated from direct circuit cell where includes NACL and KCL,and where is divided by ion exchange membrane to the positive pole and negative pole.Here is the chemical equation in reaction with KCL and NACL.

H2O--H+OH

NACL--NA=CL

NA,H,CA,Mg and metal ion move to the negative pole through membrane,OH and CL and OH-move to the positive pole .Here is a mount of bubble:

40H--4e--2H20+O2

ACL--2e--CL2

More chemical reaction

O2+H20--2e--2H+O3

C12+H2O--HCLO+CL+H

HCLO--H+CLO

It is strong killing disinfectant property because H concentration raise and show acidic property through electrolysis under PH value 2.7 and over ORP 1100mv and with O3,CL2 and HCLO.

2.Property

EOW is transparent and non-irritated-odor water without any residue,irritation and toxin,whose PH value is under 2.7 and whose ORP is over 1100mv with 80mg/l effective chlorine.

3.disinfect mechanism

3.1 ORP

The different diffusion of H+,NA+and K+in cell form ORP inside and outside of cell reaches dynamic balance with certain potential difference.From chart 1,once it touch microbe to receive electron to destroy its cell balance and change the potential difference,penetration and press to crack and overflow and change the micro organism in view of ORP-400mv-+900mvmicrobe in compare with EOW ORP+1100MV.

EOW in human body can hider the activation of enzyme to has the disinfect and sterilization function .It disappears effeciency after receiving electron because of ORP lowering.

3.2 PH value

The PH value to surviving is 3.0-10.0.Under PH value 2.7 is out of microbe living surrounding to be inactived in resemblance with the gastric juice PH value1-3.HCL in PH value2.6 is weaked than EOW,because the acid inactivating substance needs more time .So,PH value is the auxiliary index for EOW.

3.3 active oxygen

Active oxygen is unstable substance to infect through electrolyzing salt water,because of difficult reservation.EOW in 3 month reservation is still disinfectant.The main disinfect role is not active oxygen and is not stronger than EOW.

3.4 active chlorine

Chlorine has the great disinfect effect for water to kill the microbe.In room temperature,a little chlorine can irritate eye,nose and throat,but EOW is not because it has little chlorine which has a certain disinfect function.

3.5 HCLO

It can penetrate into cell to contact with enzyme to inactive microbes.EOW has the function of killing microbe in short time.Red yeast,candida albicans,bud mould and maoxuanjun in 30 seconds.Bacillus sp. In 2 minutes.HCLO need 5 minutes to kill microbes except bacillus sp.

Above all,EOW is disinfectant in the physical with the chemical measure.It can rapidly disinfect and inactive all kind of microbes.It is the disinfect with prospect.the main disinfect of EOW is ORP combined with HCLO,PH value,active oxygen and active chlorine.chemical disinfect can’t be competed with the physical in function with broad spectrum, safeness and forth.

4.the disinfect effect

4.1 it can kill staphylococcus aureus,escherichia coli and spores of bacillus subtilis out.

Killing rate of EOW is 99.99% for aureus and escherichia coli in 20 seconds,100% in 10minutes.Killing rate of EOW is 97% for spores of bacillus subtilis in 10 minutes,100% in 30 minutes.

4.2 destroy antigenicity

EOW destroys antigenicity of HBsAg in 10 seconds.

4.3 in compare with the disinfect effect of sodium hypochlorite

Here is the experiment between EOW and sodium hypochlorite that the EOW disinfect effect is better than sodium hypochlorite.Both are kill aureus,escherichia coli and spores of bacillus subtilis out in 30 seconds.EOW can kill red yeast in 2 minutes,but sodium hypochlorite not.EOW can kill candida albicans,bud mould and maoxuanjun in 30 seconds.Bacillus sp in 30 seconds,but sodium hypochlorite in 5 minutes.

5.clinic application

5.1 skin disinfect

EOW as hands disinfectant is approved by health department in Japan in 1997 to supply with automatic EOW supply system in hospital to be possible to wash hands.It is good effect to cross disinfect for medical staffs and resolve the hurt for washing hand constantly.

5.2 disinfect of endoscopes

EOW disinfect of endoscopes is judicially researched in Japan by 2 clinical experts,2 infectious disease specialists and 1expert in endoscope factory.Japan approves that it will has good disinfect effect in proper use of EOW in 1995.

The hospital has the disinfect experiment for 50 endoscopes polluted by clinic that,after organic compound treatment, it has sampled 160 times before and after disinfecting according to EOW soaking to disinfect 1 minutes (ORP1100MV,PH2.7.ACC40-50MG/L)the killing rate for endoscope separately are 99.94%,99.89%.in conclusion,after organic compound treatment,EOW will rapidly kill microbe in 1 minutes to delete many cleaning procedure by sterile water,which is the safe,effective and facile disinfect way.Here are 350 samples without harm.

5.3 blood transparent multiplexer

Blood transparent multiplexer disinfected by EOW 1008 samples,except 4 samples is not cleaned due to high PH value, appears different thrill level reaction.After treatment,it disappear.It shows that EOW disinfect is dependable,non side effect and non pollution.

5.4 disinfect air

During FLU spreading,health control department issue the notice about prevention and treatment of atypical pneumonia related technology solution that EOW can be applied into the air treatment in urgency room in hospital.

5.5 prevention from wound infection and clean

Wangguoqing concludes from 3 types of disease history:EOW is the maximum measure for clinic,which is low price,good quality and dependable effect.

5.6 change medicine for infectious wounds

EOW as the disinfectant for wounds is approved by WHO in 1994,and is applied in peace-keeping action.

5.7 apply into pregnancy

In the central hospital in inner Mongolia, here 350 case about childbirth shows that the rate of infect is 8.6% before using EOW,and the rate of infect is 0 after using it in the recovery time of non-comfort and shortness.

6.application in other industry

6.1 food and beverage industry

The disinfect rate of all tableware soaked in EOW is over 90% which is allow by internal rule.Because EOW can reduce water without residue after disinfect,it can be applied in fruits,vegetable,tofu ,fish and meat to keep them fresh.

6.2 apply in agriculture

EOW can kill plant virus.the seed soaked in EOW can raise output and release pests.It can prevent FLU from spraying

EOW to disinfect the hen house.

7.Employment

Reserve 3 days in room temperature,reserve 30 days in closet room. And reserve 90 days in cooling closet room.

8.Notices

EOW can reduce water in light,air and organic compound.It is better to use on field.the reserve material is non-metal.The metals soaking in EOW will be corroded by EOW except stainless steel.The disinfect effect can be lowered in 40 degree temperature.The polluted object is cleaned and dried to disinfect.has better select the reserve with lid and corrosion resistance and away from light.The disinfect effect of ORP is depended by time.Has better not take object to be disinfect.the disinfect time is dependable with the number of object within 30 minutes.The used EOW must be abandoned and forbid repeatedly using.

Industry Plan
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